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G2Voice Broadcast #89: All the “FDA & EPA  Approved” applications for Chlorine Dioxide and Sodium Chlorite

Sunday May 27th, 2018

10 AM CST

www.G2Voice.is

 

NEW G2Church map:

 https://genesis2church.is/contact-map

Here are some locations of our Churches are worldwide.  Contact Jordan at; This email address is being protected from spambots. You need JavaScript enabled to view it. if you want yours listed.

Note: The Head Bishops will decide who is listed and who isn’t listed. There are some that do not want to be listed due to the religious persecution of their governments. Canada, Ireland and England have aggressively tried to stop the Genesis II Church in the practice of our Sacraments. We have contacted personally the International Common Law Court of Justice(ICLCJ) in Brussels, Belgium to review these cases in their tribunal. For all those that think this isn’t a VALID court, why did Pope Francis Bergoglio, Catholic Jesuit Superior General Adolfo Pachon and Archbishop of Canterbury Justin Welby resign after found guilty of rape, torture, murder and trafficking of children. Also, Queen Beatrice of the Netherlands gave up the throne after being tried in this court? She ruled as Queen of the Netherlands from 30 April 1980 until her abdication on 30 April 2013 after convicted! Don’t believe the reason the MAINSTREAM MEDIA gives the world for these resignations. You might see the current Pope resigning soon also! http://kingdomnubia.com/2017/05/29/pope-francis-found-guilty-of-child-trafficking-rape-murder/

Note: We are in the process of submitting to this court, the International Red Cross for crimes against humanity in regard to repressing the CURE for malaria 100% of the time in 1 day or less! See: https://www.youtube.com/watch?v=FrwZN1cPfX8

FDA, CDC, EPA, DOJ are next for their crimes against humanity also! We are tired of these agencies and organizations committing crimes all over the world unchecked! No more. The Genesis II Church of Health in Healing is going to expose and drain the world swamp of these evil people! The WHO, the UN and the Bill Gates Foundation are also on our list of evil players.

 

Next Week's G2Voice Broadcast #90: Answering Common Questions about G2 Church Sacraments (6-03-2018)

 

Last week’s G2Voice Broadcast

G2Voice #088 How to get involved in ridding the world of DIS-EASE! (5-20-2018

NOTE: Spanish subtitling is being done each week now!

G2Church Seminars

Genesis 2 Church Seminar in Denver, Colorado.

Aug 18th-19th

 

It is a go!!!  We now have enough people interested in attending a Seminar in Denver, although we are still deciding where it will be held.   We will begin enrolling students this weekend.  Preregister now and receive a $50 USD discount.  The donation for the Seminar will be $450 USD once we find the location.  But if you sign up before, you will only have to donate $400 USD.  We also include a “couples” discount.   Email Bishop Jonathan at This email address is being protected from spambots. You need JavaScript enabled to view it. for more details.  

Hope to see many in attendance!!!

 

Upcoming 2 day Genesis II Church MMS seminar: Ngatea, North Island, New Zealand: 20th & 21st of July 2018.

Become a Health Minister of the Genesis II Church of Health and Healing.

Bishop Roger is conducting a 2 day training seminar in Ngatea, New Zealand; Friday the 20th and Saturday the 21st of July 2018, 9.30am to 5pm. Archbishop Mark will also be paying us a skype visit during the seminar.

The seminar will be held at Ngatea Water Gardens Function Centre, Bratlie Place, Ngatea; (approx 1 hour from Auckland and Hamilton; and one and a half hours from Tauranga).
You will learn about the sacramental protocols of the Genesis II Church of Health and Healing, and much more .… Contact for registration:
This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Israel - October?

Please let us know if you are interested in attending a G2Church Seminar in Israel! Love to share what we know and have learned with the people of Israel! Contact Jonathan at: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Newsletter signup

 http://mmsnews.is/mms-newsletter/all-newsletters-list

 

Uncensored sites we are joining

 

Here is a new video/news/uncensored site we joined as the G2Church. Please go there, join and follow us to have a voice in this Health Revolution we are in! https://oneway.com/g2church/posts

 

We have applied for membership in another NEW uncensored site to take the place of YouTube. It is called REAL.Video which will be launched worldwide July 4th by Mike Adams

Health Ranger announces Real.video as “the answer to YouTube censorship” bypass tyranny and censorship with p2p file sharing

https://www.naturalnews.com/2018-03-07-health-ranger-announces-real-video-as-the-answer-to-youtube-censorship-bypass-tyranny-and-censorship-with-p2p-file-sharing.html

 

 

You can now donate at: www.g2churchbooks.org for the PRINTED book, “Imagine, A World Without DIS-EASE Is IT Possible? In English and Portuguese now available!

This will help the Genesis II Church to do more worldwide!

NOTE: 100% of ALL donations for this VERY Informative Book go to the Genesis II Church of Health and Healing. Let’s get this book into 10’s of thousands of people around the world to open their eyes to the Truth about DIS-EASE and what to do to “restore health” from ANY DIS-EASE of the body!

NOTE: For those who access to Amazon Shipping this might be your best way to secure a copy anywhere in the world! https://www.amazon.com/Imagine-World-Without-DIS-EASE-Possible-ebook/dp/B079XSTV86/ref=dp_kinw_strp_1?dpID=41ch%252BoJFMdL&preST=_SY445_QL70_&dpSrc=detail

BUT, only 50% goes to the Church when purchased on Amazon.

 

NOTE: Spanish translation of: “Imagine, A World Without DIS-EASE” by Mark Grenon coming within the month!

 

 

 

Lifetime Membership in the Genesis II Church of Health and Healing!

 

Instead of renewing your G2 Church Membership yearly, why not pay for a lifetime emembership for a donation of 200 U.S. and be a G2 Church Member for LIFE!! For more information contact us at: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

 

Weekly Testimonies

 

  • Veszely Szilvia 1 day ago

            You are my DETOX DADDY, my HEALING HERO, GOD BLESS YOU SIR,     The World             wouldn't be the same without you guys !!!    You and Jim Humble          making a "Healed History"

 

 

  • Hello Mark,  my name is Ellen Williamson and I am 50 years old and I have been suffering with IBS, migraine and severe headaches for 25 years!   Just 4 days ago I started taking MMS after investigating the internet etc about the pros and cons.  I am overjoyed to say that all symptoms of IBS and headaches have disappeared!  I am continuing with my MMS and I am also going to start my husband on it as he has a few minor ailments such  as knee pain etc,  but for me I feel that this has saved my life!  After a recent bout of IBS where I took a violent reaction to something ingested and was ill for 11hrs,I was at my wits end.  I have tried many medications in the past, along with accupuncture, dieting, going gluten free, exercise etc but nothing gave me relief.   I can't believe that I have finally found the one thing that works for me!  I am beyond ecstatic to finally know all the suffering is now behind us.  I must also mention that my lifelong  hayfever has stopped shortly after the first dose and my skin is soft and glowing!  Over the years, I have lost faith in medical doctors as they know a little about many subjects but not enough to really treat the cause of the your illness!  Like the rest of us who have gone through the education system in Britain, we are all just brainwashed "sheeple" who only learn what the establishment wants us to know.  There is so much knowledge being withheld from the human race that could aid us greatly but cannot be monetised by the pharmaceutical industry, so they foister  their poisonous rubbish onto the unsuspecting public who have been trained to believe that the Dr knows best!  We have been paying with our health for our ignorance and lack of knowledge, but no more! With the help of people like you, we are taking back control of our lives and our health and will no longer be poisoned, lied to, or taken advantage of!  I am going to spread the word about MMS  to all my friends and family  and hopefully they will also finally find relief from their ills.  Blessings to you all at the church and please keep up the good work.  Kind regards, Ellen  from Scotland  xxx
  • No more kidney stones.

I originally purchased MMS to treat a relative with a vaccine injury, and my dad’s cancer. I have great updates to write about that later. The reason why I’m writing is because MMS healed my Kidney stones. I had my fare share of injuries from growing up to Military to my now current profession in law enforcement. Kidney Stones have been the most painful thing I’ve experienced in my life. It felt like I was giving birth out of my Johnson. It was blood in my urine and I didn’t want to drink water because peeing was so painful (of course that made things worse). Since MMS was clearing up vaccine injuries in a relative and MMS2 was clearing up bone cancer in my dad I jumped right into both. I didn’t do the starter protocol because I figured the detox side affects couldn’t be more painful than my current condition. I jumped right in to protocol 1000 using the baby bottle method, plus taking a full size 0 capsule of MMS2 twice a day. After only 2 days I was able to pee again with one full stream without stopping with minimal pain. After 3 days pain was completely gone.

I don’t know if the MMS dissolved the stone, or if it killed the infection from the stones ripping through my Johnson that got rid of the pain or both. Lord knows I’m grateful! Just being able to go to the bathroom without pain is a Blessing. Plus, it saved me from a large co-pay I avoided from not going thought a un-necessary medical procedure. Thank you, I’m saving up and look forward to meeting you in Denver

Hayes

Start slow, skip the coffee..... amazing -- Allergies gone after a few drops and a few dose. I also put some drops in my nose and ears. Brush your teeth about 5 or 6 drops activated......use the spray bottle on skin and mouth and for hygiene!

I started four days ago and I'm already feeling better I have my strength , and my sugar level has leveled out it's not so bad now and I have strength and even my voice sounds better I have tumors in my kidney and my bone and my bottom my lung. I think God has showed me this place and he's in charge and God bless you all and watch over everyone amen

 

 

G2Voice Broadcast #89: All the “FDA & EPA Approved” applications for Chlorine Dioxide and Sodium Chlorite

 

Ok, now you are going to see a big scam. I want to approach this as if I was talking to a judge and jury. The very agencies that are attacking us are admitting the safety of Chlorine Dioxide and Sodium Chlorite as are approved by FDA, EPA, CDC etc. for MANY applications. So, in other words there are companies that have paid to get approval for the same things we are doing! But, that is ok because we don’t need their approval for our SACRAMENTS and NEVER will!

 

Don’t trust Wikipedia!

 

We put up all the information we could about MMS, Sodium Chlorite and Chlorine Dioxide on Wikipedia and in 1 hour or less it was gone! I paid someone to keep putting it up for a week and it was taken down every time quickly! What are they afraid of? So, we made our own site: https://mmswiki.is/index.php/Main_Page

And our own radio broadcast: https://www.youtube.com/channel/UCQRYRsUj7A_0S36nB1haEAg

 

 

THE HISTORY OF CHLORINE DIOXIDE

1

Chlorine Dioxide:

 

The history of one of the world’s most powerful, and safest, disinfectants

1814
Sir Humphrey Davy, a British chemist, discovers chlorine dioxide (CD), a result of potassium chlorate reacting with sulfuric acid. Although he fully understood the chemistry, he most likely did not appreciate the consequences: CD will prove to be more effective at killing more viruses, bacteria and fungi than any comparable disinfectant, such as chlorine bleach.

1930s
Because of the disinfecting power of CD, use begins to grow. A major benefit of CD is that, as a true gas, it expands uniformly to fill the space it’s disinfecting. Due to concerns about the logistics of safely transporting the gas, industries wishing to use it decide to simply make it themselves in large quantities and activate it on site.

1944
To mitigate taste and odor problems, CD is introduced into a water treatment plant at Niagara Falls, N.Y. Other municipalities soon do the same. The water not only tastes better and has no unpleasant odor – it’s also safer to drink, thanks to CD’s strong disinfecting properties.

1950s
Brussels, Belgium, changes from chlorine to CD to disinfect drinking water in 1956. The 1950s see widespread use of CD in water treatment plants and swimming pools in the U.S. A new discovery is made: CD destroys biofilm, the algal slime that collects in cooling towers, among other places and harbors harmful bacteria. Chlorine bleach by contrast cannot kill biofilm.

1967
The Environmental Protection Agency (EPA) registers an aqueous form of CD for use as a sanitizer and disinfectant. Even though it aggressively attacks pathogens it is extremely safe and CD is eventually used to commercially sanitize fruit.

1970s to early 1980s
The EPA begins recommending using CD instead of chlorine bleach to treat water because CD does not produce any harmful byproducts. Although chlorine and chlorine dioxide share a common name, they are fundamentally different chemicals with distinctly different chemical structures. This means they react differently when mixed with other compounds. Chlorine bleach is formed by adding chlorine gas to salt water. However, when chlorine bleach reacts with naturally occurring organic and inorganic matter in water streams, it produces THMs (trihalomethanes). THMs have been linked to cancer. Because of its superior efficacy and how safe is its, use of CD continues to grow.

1988
The EPA registers CD as a sterilizer. This means CD is both safe and effective to use in hospitals, healthcare facilities, and laboratories.

2001
CD, in both liquid and gas forms, becomes the number one substance used to decontaminate buildings where the anthrax attacks occurred. It’s success rate is based on how well is works against very small anthrax spores, how quickly and easily it is deploy. CD completely destroys anthrax without harming buildings.

2005
CD is deployed to eradicate mold infestations in homes damages by the flood waters from Hurricane Katrina. After a 12-hour treatment, a New Orleans restaurant is able to banish all mold inside without rebuilding.

2012 (January)
ProKure revolutionizes the way CD is deployed. For the first time, because of ProKure’s patented technology, CD can be created at any time, and anywhere there’s water. It can now be safely transported in dry pouches and made into a liquid disinfectant and deodorizer on site and on demand. In essence, the ProKure product line has made it possible for industries and companies of all sizes (not just a select few) to quickly and easily unleash the amazing power of chlorine dioxide.

2014 (November)
CD is now two hundred years old. The Centers for Disease Control (CDC) registers ProKure V as a disinfectant against the Ebola virus. ProKure V begins to kill pathogens in a matter of seconds, whereas other commonly used, more traditional disinfectants take minutes. The rapid speed in which ProKure V kills pathogens makes it a product of choice for helping contain infectious-disease outbreaks and keeping public facilities cleaners and safer for everyone.

“Approved” Products using Chlorine Dioxide

 

Question: Why these companies and NOT Church sacraments?

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/orphans/2013/07/human_orphan_001218.jsp&mid=WC0b01ac058001d12b

 

2

 3

Carnebon™ 200

2% AQUEOUS STABILIZED CHLORINE DIOXIDE

https://www3.epa.gov/pesticides/chem_search/ppls/009150-00003-20180208.pdf

http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC35408

https://www.atsdr.cdc.gov/phs/phs.asp?id=580&tid=108

http://www.yourhealthremedy.com/harmful-compounds/chlorine-dioxide-side-effects/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569027/pdf/envhper00463-0059.pdf

 

https://nvlpubs.nist.gov/nistpubs/jres/68A/jresv68An3p301_A1b.pdf

·       From Food Safety Magazine - 10 Reasons Why You Should Be Using Chlorine Dioxide: https://www.foodsafetymagazine.com/magazine-archive1/februarymarch-2005/food-safety-insider-sanitation-solutions/10-reasons-why-you-should-be-using-chlorine-dioxide/

Chlorine dioxide is one powerhouse sanitizer that is getting more attention recently as food processors look for more efficacious products to help them win the sanitation battle. Approved by the U.S. Food and Drug Administration (FDA) and the U.S. Environmental Protection Agency (EPA), it is as powerful as peracetic acid and more economical, yet it has far less of an impact on the environment than quaternary ammonium salts, chlorine or bromine, making it an excellent choice for food processing plants. It costs about the same to use as other sanitizers but is more versatile and less harmful. It’s also been shown to destroy and prevent biofilms, one of the biggest challenges to food processors in destroying harmful bacteria. It also does not have the strong odor or corrosive qualities associated with chlorine.

It is a versatile alternative that can be used in many sanitation applications, including pasteurization equipment, heat exchangers, cooling towers, hard surface disinfecting, potable water treatment and deodorizing stacks in rendering plants. It is already growing in popularity as a tool to control microbiological growth in the dairy industry, the beverage industry, the fruit and vegetable processing industries, canning plants, and in poultry and beef facilities.

“Everybody in the food processing industry is looking for better cleaning and sanitation processes,” says Fred Holzhauer, Director of Business Development with Birko Corp., a leading specialty chemical manufacturer that provides a product line of more than 200 cleaning and sanitizing chemicals and application equipment to the meat, poultry, microbrewery and food industries (www.birkocorp.com).

“Chlorine dioxide eliminates sources and transfers of harmful pathogens in the food plant and attacks biofilms that form on equipment and other food-contact surfaces—all while doing less harm to the environment than other choices that do not have comparable strength.” Chlorine dioxide is the answer, says Holzhauer. Here are 10 reasons why:

1. Chlorine dioxide has 2.6 times the oxidizing power of waterborne chlorine (from bleach), giving it a wide spectrum of sanitizing uses and making it extraordinarily effective against a host of bugs. Studies have shown that it produces as high as a 6-log reduction.

2. Chlorine dioxide has a much wider pH spectrum than chlorine, making it more versatile and forgiving in a variety of application situations. Unlike chlorine, chlorine dioxide remains a true gas dissolved in solution. The lack of any significant reaction of chlorine dioxide with water is partly responsible for its ability to retain its biocidal effectiveness over a wide pH range. It also has limited reactions with organics, indicating that much more of the chlorine dioxide added to a system is available as a biocidal agent, and is not consumed to the degree that chlorine would be under the same circumstances. In addition, chlorine will react with, and be consumed by ammonia or any amine, while chlorine dioxide reacts very slowly with secondary amines, and sparingly with primary amines or ammonia.

3. Chlorine dioxide is registered with EPA (Registration No. 74986-1), and is considered an excellent bactericide, fungicide and antimicrobial agent. It has passed the EPA’s stringent DIS/TISS guidelines for use as a disinfectant and as a food-contact surface sanitizer.

4. The FDA and the U.S. Department of Agriculture (USDA) have approved stabilized sodium chlorite (a precursor) and chlorine dioxide in food processing plants for sanitizing and controlling bacteria and mold.

5. Chlorine dioxide is currently under EPA review as a surface sanitizer for E. coli O157:H7 and drug-resistant Salmonella. It is also currently under EPA review as a virucide for HIV and Hepatitis A and for use as a fungicide, virucide and algaecide.

6. Chlorine dioxide has been found to be one of the most effective tools for dispersing biofilms, and in some cases, inhibiting the formation of future biofilms. This function is especially valuable in the small cooling towers of food processing facilities where food product contamination can contribute to heavy films or algal slimes. Biofilm is a polysaccharide film or coating that protects and harbors viable bacteria colonies making surfaces more difficult to clean and disinfect.

7. Chlorine dioxide can be used on food-contact surfaces at diluted concentrations as low as 5 parts-per-million (ppm). In some cases, the compound has demonstrated a rapid kill of bacteria much less than the 30-minute period typically used in disinfection studies. Because it is so powerful in such small amounts, it is also extremely economical.

8. So far, problem cells have shown little ability to develop resistance to chlorine dioxide, as they can with other sanitizers, making it a consistent tool in the sanitation toolbox.

9. Chlorine dioxide generating systems can be used for odor control, sanitation and water purification applications. Birko Corp. offers an exclusive ClO2 generation system, which eliminates older, conventional “vacuum draw” technology, for outstanding consistency, accuracy and practical yield.

10. Unlike chlorine bleach and bromide, which make carcinogenic trihalomethanes that get washed down the drain and deposited in the environment, chlorine dioxide donates oxygen, breaking down to water, oxygen and common table salt. This makes it much less corrosive to equipment and a superb environmental choice. It also breaks down quickly, which means it won’t harm the soil or add toxic deposits to the ground.

“Chlorine dioxide has such a wide spectrum of uses,” Holzhauer says. “It’s got amazing firepower, it’s economical, and its environmental profile is safer than other choices. There’s nothing else out there that can compete.”

Source: www.birko.com

  • chemicalsafetyfacts.org

Uses & Benefits of Chlorine Dioxide

Powerful Disinfection in Water Treatment

Chlorine dioxide is a disinfectant. When added to drinking water, it helps destroy bacteria, viruses and some types of parasites that can make people sick, such as Cryptosporidium parvum and Giardia lamblia.

Personal Care Products

Personal hygiene applications for chlorine dioxide include mouthwash, toothpaste and contact lens cleaners. Chlorine dioxide is used in dentistry as an oxidizing biocide compound to treat bad breath.

Industrial/Manufacturing Uses

Chlorine dioxide chemistry is used in a wide variety of industrial, oil and gas, food and municipal applications:

Food and Beverage Production
Chlorine dioxide can be used as an antimicrobial agent in water used in poultry processing and to wash fruits and vegetables.

Medical Applications
In hospitals and other healthcare environments, chlorine dioxide gas helps to sterilize medical and laboratory equipment, surfaces, rooms and tools. Researchers have found that at appropriate concentrations, chlorine dioxide is both “safe and effective” at helping to eliminate Legionella bacteria in hospital environments, as well as Legionnaires’ disease, a potentially deadly type of pneumonia caused by the Legionella pneumophila bacteria.

Other Industrial Uses
Chlorine dioxide used in oil and gas disinfection applications can help increase well performance and also combat oil souring and protect other fluids from spoilage. Chlorine dioxide is used in the electronics industry to clean circuit boards and as a bleach in the paper and textile manufacturing processes.

Safety Information

According to U.S. Centers for Disease Control and Prevention, chlorine dioxide is added to drinking water to protect people from waterborne pathogens. Chlorine dioxide is used to disinfect drinking water around the world and is approved for use by the Environmental Protection Agency (EPA) and included in the World Health Organization’s (WHO) Guidelines for Drinking-water Quality. The U.S. Food and Drug Administration (FDA) also has approved the use of chlorine dioxide in certain food applications as well as in over-the-counter and prescription drugs.

In its pure form, chlorine dioxide is a hazardous gas but most people are “not likely” to breathe air containing dangerous levels of chlorine dioxide as it does not occur naturally in the environment. For workers who use chlorine dioxide, the U.S. Occupational Safety and Hazard Administration (OSHA) regulates the level of chlorine dioxide in workplace air for safety. OSHA has set a Permissible Exposure Limit (PEL) for chlorine dioxide at 0.1 parts per million (ppm), or 0.3 milligrams (mg) per cubic meters (m3) for workers using chlorine dioxide for general industrial purposes. OSHA also has a PEL for chlorine dioxide for the construction industry. Chlorine dioxide is always made at the location where it is used.

https://www.chemicalsafetyfacts.org/chlorine-dioxide/

Chlorine Dioxide (aka MMS) Registered by the FDA for MRSA Prevention Protocol

The EPA (Environmental Protection Agency) has recently registered a new product for preventing and eliminating methicillin-resistant Staphylococcus aureus (MRSA), which causes potentially deadly infections commonly known as “staph” infections. The MRSA “super bug” is typically contracted in hospitals, in other healthcare environments, and in health clubs and locker rooms.

The EPA has registered Selectrocide chlorine dioxide for use as a disinfectant on hard, non-porous surfaces and instruments, including those used within hospitals and other medical settings. As a no-wipe, no-rinse spray, Selectrocide chlorine dioxide can also be used on hard, non-porous surfaces in health clubs, spas, public places and swimming facilities as a treatment against MRSA. The EPA has also registered Selectrocide as a disinfectant for vancomycin-resistant Enterococcus faecalis, athlete's foot, Mycobacterium bovis (TB) and other pathogens that spread in many environments.

MRSA is usually spread by direct physical contact with those already infected or through indirect contact by touching objects (towels, clothes, sports equipment, etc.) that infected skin has contaminated. Consequently, any heavily trafficked area can be a source of infection.

According to a report by the BBC News, “Staphylococcus aureus is the leading cause of human infections in the skin and soft tissues, bones and joints, abscesses and normal heart valves. It flourishes in the hospital setting, producing bloodstream and surgical wound infections, including MRSA.” (news.bbc.co.uk/1/hi/health/4671585.stm)

HOW SELECTROCIDE KILLS MRSA AND OTHER DEADLY PATHOGENS

Selectrocide is greater than 99% pure chlorine dioxide, an ideal biocide because of its ability to kill viruses, bacteria, fungi, and algae at low saturation levels (parts per million) in a manner that does not allow pathogens to build resistance to the compound.

Prior to Selectrocide, healthcare and health club environments were limited to using substances like bleach and quaternary ammonium compounds that can leave residue and require higher concentrations than does chlorine dioxide to achieve the same antimicrobial efficacy.

Selectrocide's chlorine dioxide is produced in water and sprayed, mopped, or sponged onto surfaces that require disinfection. After application, the solution is left on target surfaces and does not require rinsing. Due to the comparatively low application concentrations required to kill pathogens, Selectrocide is compatible with most materials.

THE DEVELOPMENT OF MRSA AND ITS INCREASING RESISTANCE TO ANTIBIOTICS

Staphylococcus aureus (SA)-Antibiotic Resistance (General): Throughout history, Staphylococcus aureus (SA) has been a dangerous pathogen once it has successfully breached the normal defense system. The first effective antibiotic against SA, penicillin, became available in the 1940s. Soon after, SA evolved resistance to penicillin, and by the late 1950s, 50 percent of all SA strains were resistant. Today, fewer than 10 percent of SA infections can be cured with penicillin.

The next weapons against SA, methicillin and cephalosporin, became available in the 1960s and 1970s. By the late 1970s, some strains of SA had evolved resistance to these drugs. Today, as many as 50 percent of SA strains isolated from U.S. hospitals are resistant to methicillin. (Source: National Institutes of Health)

GENERAL BACKGROUND INFORMATION ON CHLORINE DIOXIDE AND SELECTROCIDE

Chlorine dioxide is effective at low concentrations across a wide range of pH (roughly 4 to 9), and, because it is a gas in its natural state, dissipates upon exposure to sunlight As a consequence, it is known widely as one of the most effective inhibitors of algae, yeast, mold, fungi and viruses. However, because transporting the gas is prohibited in all but frozen forms, pure chlorine dioxide has heretofore been limited to use in large concerns that employ chemical generators, such as pulp mills (controlling slime) and municipal water systems (water purification applications).

Similarly, in cleaning and antimicrobial knockdown applications, pure chlorine dioxide has been unavailable, and only with “stabilized” solutions or acidified sodium chlorite, which are corrosive and produce significant chemical residues, could any of the advantages of chlorine dioxide be realized.

JUST ADD WATER — AND WAIT. Now, Selectrocide brings the power of greater than 99% pure chlorine dioxide solutions to point-of-use applications. Selectrocide produces chlorine dioxide simply by submersing the product in water. The resulting chlorine dioxide solution can be used to kill disease-bearing bacteria, yeasts, molds, fungi and algae using spraying, washing or “dip” cleaning methods.

Selectrocide makes it possible-for the first time-to generate specific concentrations of chlorine dioxide at the point of use, at neutral pH and with very low residuals, using only tap water.

SUMMARY OF SELECTROCIDE BENEFITS

US EPA-registered as a disinfectant against MRSA, and other potentially virulent pathogens.

  • Pathogens cannot build up resistance to Selectrocide because it kills harmful organisms by breaking down cell walls.
  • Easy to use and does not require HAZMAT or complicated equipment
  • Can be made on-site in specific quantities and in concentrations desired. Only tap water is required to generate the chlorine dioxide.
  • Because it kills pathogens with such efficacy, Selectrocide may reduce costs because fewer disinfection treatments may be required during a given maintenance and cleaning cycle.

Source: http://www.healthfreedoms.org/new-mrsa-bacteria-killer-chlorine-dioxide-aka-activated-mms-registered-by-epa/

  • Food Processing. Using a distinctive concentration of chlorine dioxide it provides specific microbiological control for the food and beverage industry, such as brewing and bottling, washing fruit and vegetables, poultry and meat processing, fish processing and dairy plants.

Using a distinctive concentration of chlorine dioxide it provides specific microbiological control for the food and beverage industry, such as brewing and bottling, washing fruit and vegetables, poultry and meat processing, fish processing and dairy plants. Chlorine dioxide does not react with most “organics” in flume water; this makes it a very effective disinfectant. It is also an excellent odor neutralizer, helping to neutralize foul smelling odors including secondary and tertiary amines formed in the meat packing industry.

A list of possible markets to apply Dutrion products are:
  • Fruit and vegetable processing.
  • Poultry processing.
  • Food contact paper manufacture.
  • Cleaning pasteurizers, warmers and coolers.
  • Disinfection of packing operations.
  • Flume water control.
  • Water treatment.
  • Equipment disinfection.
  • Disinfection of tankers, vehicles and transportation vessels.
Cleaning in place (CIP) and sanitizing operations

Active chlorine dioxide can be very effective when used as the final sanitizing rinse in CIP systems, including filler rooms. Typically applied at low concentrations with a short contact time. It leaves no toxic residues to interfere with other chemical/biochemical processes. Chlorine dioxide works quickly and breaks down into inert compounds. Its unique chemistry produces no toxic by-products (such as THM’s) and is therefore an environmentally friendly alternative to traditional sanitizers.

Other examples of sanitizing applications for Dutrion products are:
  • Cleaning pasteurizers, bottle/can warmers and coolers.
  • Chain and conveyor spray in bakeries.
  • Crate washing, bottle wash, staff hand wash.
  • Water purification and disinfection of water distribution and storage tanks.
  • Mould and odor control with Dutrion or DutriGel.
  • Sanitation of tanker trucks, wagons and transportation vessels.

Source: http://dutrion.com/chlorine-dioxide-food-processing/

 

The Myths and Misconceptions of Chlorine Dioxide Gas

 

Tue, 09/03/2013 - 8:27pm

by Kevin Lorcheim

Learn the truth about its properties, behaviors, and abilities.

Did you know that Christopher Columbus wasn’t trying to prove that the Earth was round when he set sail in 1492? Did you know that toilet water does not spin in different directions in the northern and southern hemispheres? How about that Paul Revere didn’t shout “The British are coming?” Even in this age of information, sometimes we believe in things that just aren’t true. Such is the case with chlorine dioxide.

There is much confusion and conflicting information regarding its properties, behavior, and abilities. Some of the misinformation comes from old experiences, not aware that the technology has advanced. Other times it stems from misinterpretations, attributing certain outcomes to chlorine dioxide rather than the true source. Whatever the reason, it’s time to finally understand the truth about chlorine dioxide.

Myth: Chlorine Dioxide Corrodes Stainless Steel
This myth originated due to some commonly used liquid chlorine dioxide products. These liquid solutions are produced by mixing a base and activator which create liquid chlorine dioxide as well as chlorous acid and acidified sodium chlorite. It is these acidic byproducts which can cause corrosion of stainless steels. Chlorine dioxide itself has been shown to be compatible with stainless steel through exposure studies using the pure, gaseous form.

Myth: Chlorine Dioxide Forms Hydrochloric Acid in Water
Chlorine dioxide does not form hydrochloric acid when mixed with water. This myth originates from the false association between chlorine and chlorine dioxide, as chlorine does form hydrochloric acid when mixed with water. Just as carbon is different than carbon dioxide, chlorine is different than chlorine dioxide. While there are similarities between chlorine and chlorine dioxide, such as their similar smell, they do have different properties. Also among their differences, chlorine dioxide gas does not deplete the ozone layer as chlorine gas does.

Water with pure chlorine dioxide in it would still have a neutral pH. Chlorine dioxide gas does not react with water and stays as chlorine dioxide within the water. This enables it to kill organisms within the water, as well as any on the surface beneath the water. This trait is unique to chlorine dioxide among decontaminating fumigants, as hydrogen peroxide dilutes in water and cannot kill organisms in or beneath the water.

Misconception: Chlorine Dioxide is Explosive
There is truth to the notion that chlorine dioxide can be explosive. The misconception that chlorine dioxide is explosive comes from knowing only half of the truth. The concentration at which chlorine dioxide gas is used is 250 times less than the explosive threshold. This makes the risk of explosion ZERO as explosive concentrations cannot be achieved.

Myth: Chlorine Dioxide is More Corrosive than Hydrogen Peroxide
Both chlorine dioxide and hydrogen peroxide are oxidizers and can be corrosive on sensitive materials. The myth that chlorine dioxide is more corrosive than hydrogen peroxide is attributed to the common usage of liquid chlorine dioxide solutions, which as stated earlier have acidic byproducts which are more destructive than chlorine dioxide itself. Most comparisons and publications pertaining to chlorine dioxide involve the same liquid chlorine dioxide products. Very few chlorine dioxide products utilize a pure chlorine dioxide, but when they do they are both scientifically and statistically less corrosive than hydrogen peroxide as exhibited in Figures 1 and 2.

Hydrogen peroxide is injected as a vapor into the space being decontaminated having a 35% hydrogen peroxide/ 65% water composition. When the vapor condenses due to the space being cooler than its 228˚F boiling point, the condensate’s hydrogen peroxide concentration jumps from 35% to 78%. This increase in concentration adds to hydrogen peroxide’s corrosive nature, as noted in its incompatibility with some epoxy finishes on walls and flooring as well as other materials.

Figure 2 shows data from a U.S. EPA study on the material compatibility of hydrogen peroxide vapor and chlorine dioxide gas. Computers were tested for functionality after repeated exposures to both agents. Results show that over time, computers exposed to hydrogen peroxide vapor exhibited more failures than those exposed to chlorine dioxide gas.

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5

Myth: Chlorine Dioxide Leaves Residues
The myth that chlorine dioxide leaves a residue is yet another that originates via the generalization between all chlorine dioxide products. Just as two refrigerators can have different features, so can chlorine dioxide products. Some of the liquid chlorine dioxide products can leave a residue, necessitating a post-treatment rinse. This residue is attributed to the nature of the product and its composition.

A pure chlorine dioxide gas does not leave a residue, as one of the first commercial uses of pure chlorine dioxide gas was for the sterilization of implantable contact lenses. In order for the process to be approved by the FDA, it had to be shown that pure chlorine dioxide gas did not leave a residue.

Myth: Chlorine Dioxide is a Carcinogen
The origin of this myth is unknown, as there is no evidence that chlorine dioxide is a carcinogen. Chlorine is not a carcinogen either, eliminating the association between chlorine and chlorine dioxide as the potential source as well. Chlorine dioxide can be found in toothpastes and mouthwashes. It is used to treat drinking water and to rinse various fruits, vegetables, and meats, making claims of its status as a carcinogen baseless.

Myth: Chlorine Dioxide Gas is More Dangerous than Hydrogen Peroxide Vapor
Chlorine dioxide gas is used safely every day to decontaminate rooms, suites, and other spaces. The myth that it is more dangerous than hydrogen peroxide vapor comes from its lower OSHA 8-hr safety level. The consumer use of hydrogen peroxide also leads to its perception as being safer than chlorine dioxide, even though most are aware that using 35% commercial grade hydrogen peroxide on cuts and scrapes would be painful. The truth however, is that neither chlorine dioxide nor hydrogen peroxide are inherently safe. All decontaminating agents are dangerous and lethal, which is why they are used for decontamination. Chlorine dioxide has a 0.1ppm 8-hr safety level while hydrogen peroxide’s level is 1ppm. Both are used at concentrations over a hundred times greater than their safety levels, so exposure to either is dangerous. Chlorine dioxide gas, however, does have properties which help reduce the risk of danger to humans. Chlorine dioxide gas has an odor similar to chlorine, and can be sensed below 0.1ppm. This acts as an alert in case of a leak, as personnel is aware of the leak at very low levels, allowing them to act upon it as they deem fit (either aborting the process or fixing the leak). Hydrogen peroxide cannot be smelled, and any leakage cannot be identified by nearby personnel. This allows the leakage and exposure to personnel to continue and worsen.

The other property which aids in the safety of the chlorine dioxide process is its status as a true gas. As it does not condense on surfaces, in case of emergency the gas can be aerated down from full concentration to safe levels in 12–15 air exchanges, or about 30 minutes. Hydrogen peroxide is a liquid at room temperature and therefore condenses on surfaces. This condensate takes much longer to dry and aerate from a space, needing hours if not overnight before it is safe to be in that space. This means that in the event of leakage, chlorine dioxide gas can be removed making the area safe in 30 minutes or less, while hydrogen peroxide can take until the next day.

Myth: Chlorine Dioxide Gas Cannot be Contained
This myth is based on the distributive properties of chlorine dioxide gas. A benefit of chlorine dioxide is that it is a true gas at room temperature. As a true gas, it expands to uniformly fill the space it is contained within. This gives it the natural ability to contact all surfaces within a space in equal concentrations, guaranteeing an even level of kill throughout the space. Its small molecule size coupled with this distributive ability allows the gas to penetrate small cracks and crevices. This penetrative capability is the basis of the myth that chlorine dioxide gas cannot be contained. In truth chlorine dioxide is contained in the same fashion as formaldehyde and hydrogen peroxide vapor, the other two commonly used fumigants. To contain them, the spaces are isolated from the HVAC system and the doors and other openings and penetrations are sealed using tape or other means.

This myth also has ties to the fact that chlorine dioxide has a smell and hydrogen peroxide does not. Due to the inability to smell hydrogen peroxide, users might not be aware of leakages as they would with chlorine dioxide gas. This contrast in awareness of leaks can give users the false notion that chlorine dioxide cannot be contained as easily as hydrogen peroxide can when in fact it just illustrates the danger of hydrogen peroxide.

Conclusion
In the age of the internet, when information of all kinds is easily accessible, it’s hard to imagine that so many myths and misconceptions can exist. Part of this is because while it is easy to find answers, it can be more difficult to find the truth. For instance, Christopher Columbus and most of the other educated folk in his time knew the earth was round as Pythagoras had written about a round earth as early as the sixth century B.C. It was proven by a host of others including Aristotle and Ptolemy by the 2nd century A.D., over 1,300 years before Columbus set sail.

While it is somewhat hard to understand how some of these myths have lasted hundreds of years, the myths and misconceptions regarding chlorine dioxide are decidedly newer and more understandable that they are believed. Many of the myths surrounding chlorine dioxide deal with corrosion and its material compatibility. These myths primarily stem from the common use of various liquid chlorine dioxide products and the corrosive byproducts that are sprayed, wiped, and fogged alongside the chlorine dioxide. These misconceptions also stem from the incorrect comparisons to chlorine, which is similar in name and smell but little else. Like many myths, they are often based on a truth that got twisted along the way.

Kevin Lorcheim is an Engineer for ClorDiSys Solutions, Inc. (908) 236-4100; www.clordisys.com.

 

Sodium chlorite administration in long-Evans rats: Reproductive and endocrine effects

Long-Evans rats, 4–6 weeks of age, were given access to 0, 1, 10, or 100 ppm sodium chlorite in deionized water ad libitum as drinking water. Males were exposed 56 days, and females for 14 days prior to breeding and throughout the 10-day breeding period. Males were evaluated for sperm parameters and reproductive tract histopathology following the breeding period. Females were exposed throughout gestation and lactation. Dams and pups were necropsied at weaning. Decreases in serum T3 and T4 were observed on Postnatal Days 21 and 40 in male and female pups exposed to 100 ppm chlorite or above. Additionally, groups of males were exposed to 0, 10, 100, or 500 ppm ad libitum in the drinking water to confirm observed subtle reproductive effects and examine dose-effect relationships. A significant increase in the percentage of abnormal sperm morphology (P < 0.001) and decrease in sperm direct progressive movement (P < 0.01) were observed for adult males at chlorite levels of 100 or 500 ppm. Since other clinical and reproductive endpoints were not affected, sperm morphology and sperm direct progressive movement may be two of the more sensitive indicators of reproductive damage.

Source: https://www.sciencedirect.com/science/article/pii/S0013935187800257

  • Shi and Xie (1999) indicated that an acute oral LD50 value (a dose expected to result in death of 50% of the dosed animals) for stable chlorine dioxide was >10,000 mg/kg in mice.

Chlorine Dioxide & Chlorite - Agency for Toxic Substances and ...

https://www.atsdr.cdc.gov/toxprofiles/tp160-c3.pdf

·     Ten-week Whole-body Inhalation Toxicity Study of Chlorine Dioxide Gas in Rats

Abstract

Chlorine dioxide (ClO2) gas can protect against influenza virus infection at a concentration of 0.03 parts par million (volume/volume), which is believed to be nontoxic in humans. This suggests an opportunity for the development of a novel protective method against airborne infectious diseases. This method is especially applicable to the highly pathogenic H5N1 influenza virus, as there is currently no safe and effective protection against H5N1. However, concerns remain regarding the safety of ClO2 gas for protection against virus infection, especially whether a concentration of 0.03 parts per million is really non-toxic when it is used for humans in closed or semiclosed spaces. In view of the importance of the usefulness and necessity of low concentration ClO2 gas treatment, it is critical to determine the “no observed adverse effect level” (NOAEL) of ClO2 gas. In 1972 Paulet and Desbrousses reported that the “lowest observed adverse effect level” (LOAEL) of ClO2 gas was 1 part per million. We attempted to confirm their data under carefully designed experimental conditions. Here, we performed a rat hole-body inhalation toxicity study, where rats were exposed to 1 part per million ClO2 gas for 5 hours per day and 5 days per week over a period of 10 weeks. The rats were exposed to a meticulously controlled low-concentration ClO2 gas. No adverse effect was observed under these experimental conditions in contrast to the study by Paulet and Desbrousses. We conclude that the no observed adverse effect level of ClO2 gas at these experimental conditions is 1 ppm. We hope this result will help develop a preventive method against airborne microbial infectious diseases of humans.

https://www.omicsonline.org/tenweek-wholebody-inhalation-toxicity-study-of-chlorine-dioxide-gas-in-rats-2157-7609-4-143.php?aid=12171

Australian Government Admits Chlorine Dioxide Works?

 http://www.npi.gov.au/resource/chlorine-dioxide

Description

The major use of chlorine dioxide is as a bleach in a number of industries: in cleaning and de-tanning of leather, and as a bleaching agent for wood pulp, fats and oils, cellulose, flour, textiles, and beeswax.

Chlorine dioxide is registered as a bactericide, fungicide and algaecide. It is used to disinfect human drinking water systems, commercial water cooling tower systems, and metal cutting fluids. It may also be used to disinfect dairy farm animals and milking equipment, in eating establishments and food processing/handling areas and around the house. It is used extensively in Europe for disinfecting drinking water, and its use there is increasing as well as in North America and Australia, as an alternative to chlorine due to lesser problems with disinfection by-products.

Approved food additive in Australia (No. 926).

Substance details

Substance name: Chlorine dioxide

CASR number: 10049-04-4

Molecular formula: ClO2

Synonyms: chlorine peroxide; chloroperoxyl; doxcide 50; chlorine oxide; chlorine(IV) oxide

Physical properties

Chlorine dioxide is a strongly oxidising, yellow to reddish-yellow gas or liquid with a pungent, sharp odour. The odour is similar to that of chlorine and nitric acid. Soluble in water, alkaline, and sulfuric acid solutions. It is normally supplied as a less than 10% solution in cold water.

Melting Point: -59°C

Boiling Point: 11°C

Specific Gravity: 3.09

Vapour Density: 2.3

1 ppm = 2.8 mg/m3
Formula mass 67.452

Chemical properties

Chlorine dioxide gas is flammable, and is violently explosive in air at concentrations over 10%. It can be ignited by almost any form of energy, including sunlight, heat, or sparks. Chlorine dioxide is strongly oxidising, and reacts violently with organic chemicals and can be detonated by sunlight, heat, or contact with mercury or carbon monoxide.

Description

Acute health effects: The following acute (short-term) health effects may occur immediately or shortly after exposure to chlorine dioxide: irritate the nose and throat, causing coughing and chest pain; eye irritation with watery eyes and seeing halos around lights; breathing chlorine dioxide can irritate the lungs causing coughing and/or shortness of breath. Higher exposures can cause a build-up of fluid in the lungs (pulmonary oedema), a medical emergency but which might not occur for 24 hours, with severe shortness of breath and possibly death.

Chronic health effects: The following chronic (long-term) health effects can occur at some time after exposure to chlorine dioxide and can last for months or years: irritate the lungs; repeated exposure may cause bronchitis to develop with cough, phlegm, and/or shortness of breath. Permanent lung damage may occur, especially with repeated exposure to the vapours. There is limited evidence that chlorine dioxide may damage the developing foetus.

Entering the body

The substance can be absorbed into the body by inhalation, ingestion of food that has been treated with chlorine dioxide, or skin contact.

Exposure

People living near industries that produce or use chlorine dioxide. From using disinfectants or bleaches that contain chlorine dioxide. From foods and drinking water that have been treated with chlorine dioxide.

Health guidelines

Australian Drinking Water Guidelines (NHMRC and ARMCANZ, 1996):
Maximum of 1 mg/L (i.e. 0.001 g/L)

Worksafe Australia:
Maximum time weighted exposure (TWA) level: 0.1 ppm 0.28 mg/m3
Maximum short term exposure level (STEL): 0.3 ppm 0.83 mg/m3

Description

Chlorine dioxide is well established to be harmful to all forms of life. Ranked in the USA as one of the most hazardous compounds (worst 10%) to ecosystems.

Entering the environment

Most releases will be as the gas to the atmosphere or in wastewater streams from plants that make or use chlorine dioxide. Because of its high reactivity chlorine dioxide will not persist long in the air, water, or soil environments - up to minutes in air and up to hours in the others.

Where it ends up

In the atmosphere it will photolyze rapidly, with a tropospheric half-life of a few seconds. Because of its high reactivity, chlorine dioxide will breakdown rapidly in natural waters (that is, waters that contain moderate amounts of organic matter). Nevertheless, this substance is considered hazardous to the environment with special attention required for water organisms.

The breakdown products are chloride ion and oxidised products of organic matter.

Environmental guidelines

No national guidelines.

Industry sources

Paper and allied products industries; textile mills; chemical industries: food processing industries; drinking water treatment plants; and commercial water-cooling tower systems.

Diffuse sources, and industry sources included in diffuse emissions data

Residues from food and drinking water that have been treated with chlorine dioxide.

Natural sources

No specific information. Because of the nature of its high chemical reactivity, it is unlikely to occur naturally.

Transport sources

None known.

Consumer products

Possibly in some disinfectants and bleaches. Foods and drinking water that have been treated with chlorine dioxide.

Sources used in preparing this information

  • Australian and New Zealand Environment and Conservation Council (ANZECC) (1992), Australian Water Quality Guidelines for Fresh and Marine Waters.
  • CalEPA Air Resources Board Toxic Air Contaminant Summary (accessed, June, 1999)
  • ChemFinder WebServer Project (1995) (accessed, June, 1999)
  • Environmental Defense Fund - Summary, Uses, Consumer Products, Rank (industrial, by quantity) (accessed, June, 1999)
  • IPCS International Chemical Safety Card (accessed, June, 1999)
  • Meagher, D (1991), The Macmillan Dictionary of The Australian Environment, Macmillan Education Australia Pty Ltd.
  • National Environment Protection Council (1998), National Environment Protection Measure for the National Pollutant Inventory. (accessed, March, 1999)
  • National Health and Medical Research Council (NHMRC) and Agriculture and Resource Management Council of Australia and New Zealand (ARMCANZ) (1996), Australian Drinking Water Guidelines.
  • New Jersey Health and Safety (accessed, June, 1999)
  • Richardson, M (1992), Dictionary of Substances and their Effects, Royal Society of Chemistry, Clays Ltd, England.
  • Sax, N.I. Dangerous Properties of Industrial Materials. 6th Ed. Van Nostrand Reinhold. New York. 1984. pp. 1505-1506.
  • Sittig, M (1991), Handbook of Toxic and Hazardous Chemicals and Carcinogens, 3rd edition, Noyes Publications, USA .
  • Technical Advisory Panel (1999), Final Report to the National Environment Protection Council.
  • US Department of Health and Human Services (1990), NIOSH Pocket Guide to Chemical Hazards, Publication No. 90-117.
  • USEPA Integrated Risk Information System Report (accessed, June, 1999)
  • USEPA Toxic Release Inventory Fact Sheet (accessed, June, 1999)

Worksafe Australia (accessed, June, 1999)

 


FDA Approved Chlorine Dioxide

https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=173.300

[Code of Federal Regulations]

[Title 21, Volume 3]

[Revised as of April 1, 2017]

[CITE: 21CFR173.300]

TITLE 21--FOOD AND DRUGS

   

CHAPTER I--FOOD AND DRUG ADMINISTRATION
DEPARTMENT OF HEALTH AND HUMAN SERVICES

 
 

SUBCHAPTER B--FOOD FOR HUMAN CONSUMPTION (CONTINUED)

 

PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION

Subpart D--Specific Usage Additives

Sec. 173.300 Chlorine dioxide.

 

Chlorine dioxide (CAS Reg. No. 10049-04-4) may be safely used in food in accordance with the following prescribed conditions:

(a)(1) The additive is generated by one of the following methods:

(i) Treating an aqueous solution of sodium chlorite with either chlorine gas or a mixture of sodium hypochlorite and hydrochloric acid.

(ii) Treating an aqueous solution of sodium chlorate with hydrogen peroxide in the presence of sulfuric acid.

(iii) Treating an aqueous solution of sodium chlorite by electrolysis.

(2) The generator effluent contains at least 90 percent (by weight) of chlorine dioxide with respect to all chlorine species as determined by Method 4500-ClO2 E in the "Standard Methods for the Examination of Water and Wastewater," 20th ed., 1998, or an equivalent method. Method 4500-ClO2 E ("Amperometric Method II") is incorporated by reference in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. You may obtain a copy from the Office of Food Additive Safety (HFS-200), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5001 Campus Dr., College Park, MD 20740, or the American Public Health Association, 800 I St. NW., Washington, DC 20001-3750. You may inspect a copy at the Food and Drug Administration's Main Library, 10903 New Hampshire Ave., Bldg. 2, Third Floor, Silver Spring, MD 20993, 301-796-2039, or at the National Archives and Records Administration (NARA). For information on the availability of this material at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html.

(b)(1) The additive may be used as an antimicrobial agent in water used in poultry processing in an amount not to exceed 3 parts per million (ppm) residual chlorine dioxide as determined by Method 4500-ClO2 E, referenced in paragraph (a)(2) of this section, or an equivalent method.

(2) The additive may be used as an antimicrobial agent in water used to wash fruits and vegetables that are not raw agricultural commodities in an amount not to exceed 3 ppm residual chlorine dioxide as determined by Method 4500-ClO2 E, referenced in paragraph (a)(2) of this section, or an equivalent method. Treatment of the fruits and vegetables with chlorine dioxide shall be followed by a potable water rinse or by blanching, cooking, or canning.

[60 FR 11900, Mar. 3, 1995. Redesignated at 61 FR 14245, Apr. 1, 1996, as amended at 61 FR 14480, Apr. 2, 1996; 63 FR 38747, July 20, 1998; 65 FR 34587, May 31, 2000; 70 FR 7396, Feb. 14, 2005; 81 FR 5592, Feb. 3, 2016]


Cell apoptosis inducer containing chlorine dioxide and use thereof in preparing cosmetics or anti-aging or antineoplastic drugs

https://www.google.com/patents/WO2016074203A1?cl=en

Note: This is a exceprt from the above article.

Patents The present invention relates to a cell apoptosis inducer containing chlorine dioxide.

Abstract


The present invention relates to a cell apoptosis inducer containing chlorine dioxide. The present invention relates to a cell apoptosis inducer kit containing the following two independent components: the first component: a chlorine dioxide precursor solid, or a solution containing a chlorine dioxide precursor; and the second component: an auqeous solution of an acidity pH adjuster; the two components are stored separately, and can be mixed before use so that in-situ reaction occurs and the cell apoptosis inducer containing chlorine dioxide is prepared; and the amounts and concentrations of the first component and the second component enable the pH of the mixed solution to be 1.5-6.5. The present invention further relates to use of the cell apoptosis inducer containing chlorine dioxide or the cell apoptosis inducer kit containing chlorine dioxide in preparing drugs for treating tumors, or use thereof in preparing anti-aging drugs for target tissues of mammals, or use thereof as cosmetics, or use thereof in preparing chemotherapeutic drugs.

Claims(8)  translated from Chinese

  • Chlorine dioxide comprising the inducer of apoptosis.
  • Apoptosis inducer as claimed in claim 1, which comprises dissolving in water chlorine dioxide in which chlorine dioxide concentration is 500-2900ppm, based on the calculated mass.
  • Apoptosis inducer as claimed in claim 2, further comprising an acidic pH adjusting agent, an apoptosis inducing agent such that the pH = 1.5-6.5, said at least one acidic pH adjusting agent is selected from the following collection:

An organic acid or a salt thereof selected from formic acid, acetic acid, propionic acid, butyric acid, lactic acid, pyruvic acid, citric acid, malic acid, tartaric acid, gluconic acid, glycolic acid, fumaric acid, malonic acid, maleic acid , a collection of oxalic acid, succinic acid, acrylic acid, crotonic acid, glutaric acid, and salts thereof;

Inorganic acid or salt thereof, selected from hydrochloric acid, the set consisting of phosphoric acid, boric acid, metaphosphoric acid, pyrophosphoric acid, sulfamic acid, dihydrogen phosphate, hydrogen phosphate.

  • Apoptosis inducer as claimed in claim 3, wherein said pH adjusting agent is selected from citric acid, acetic acid or dihydrogen phosphate.
  • Comprising chlorine dioxide apoptosis-inducing agent to a kit comprising two separate components:

First component: a solid body before the chlorine dioxide or chlorine dioxide comprising the front body solution;

Second Component: an aqueous solution of acidic pH adjusting agent;

Both stored separately, and can be mixed before use, and prepared on-site response contains chlorine dioxide apoptosis inducing agent; and the amount and concentration of the first component and a second component enables the mixed solution the pH = 1.5-6.5;

Wherein at least one member selected from chlorine dioxide before the sodium chlorite, potassium chlorite, chlorite, lithium chlorite, calcium chlorite, magnesium chlorite or barium;

Wherein said acidic pH adjusting agent is selected from the following set of at least one of:

An organic acid or a salt thereof selected from formic acid, acetic acid, propionic acid, butyric acid, lactic acid, pyruvic acid, citric acid, malic acid, tartaric acid, gluconic acid, glycolic acid, fumaric acid, malonic acid, maleic acid , a collection of oxalic acid, succinic acid, acrylic acid, crotonic acid, glutaric acid, and salts thereof;

Inorganic acid or salt thereof, selected from hydrochloric acid, the set consisting of phosphoric acid, boric acid, metaphosphoric acid, pyrophosphoric acid, sulfamic acid, dihydrogen phosphate, hydrogen phosphate.

  • Containing chlorine dioxide apoptosis inducer kit 5 or apoptosis-inducing agent as claimed in any one of claims 1-4 claim 1 for the manufacture of a medicament for inducing apoptosis of.
  • One of claims 1-4 or apoptosis inducers containing chlorine dioxide as claimed in claim any one of Claims comprising chlorine dioxide apoptosis inducer kit 5 Preparation of a medicament for the treatment of tumors of the use, or for Preparation of a mammalian target tissue for anti-aging drug use, or as cosmetic purposes, or for the preparation of chemotherapeutic agents.
  • Use of claim 7, wherein the tumor comprises: brain metastases, meningiomas, tumors of the skull, brain, pituitary adenomas, acoustic neurinoma, glioma, brain tumor; maxillary sinus cancer, laryngeal cancer, nasopharyngeal cancer, tongue cancer, thyroid cancer, gum cancer, lip cancer; thymoma, lung cancer, adenocarcinoma, breast, sarcoma, lung metastases, breast fibroids, breast cancer; pancreatic cancer, stomach cancer, gallbladder cancer, colorectal cancer, pancreatic cancer, esophageal cancer, colon cancer, liver cancer; renal pelvis cancer, penile cancer, urothelial carcinoma, prostate cancer, urinary tract cancer, testicular cancer, bladder cancer, Wilms tumor, renal cell carcinoma; ovarian cancer, fallopian tube cancer, vulvar cancer , vaginal cancer, uterine cancer, cervical cancer, choriocarcinoma, pelvic cancer; skin cancer, liposarcoma, malignant teratoma, fibroma, neurofibroma, melanoma, cholangiocarcinoma, squamous cell carcinoma, basal cell carcinoma; chordoma , bone, cartilage, osteosarcoma, synovial sarcoma, giant cell tumor, fibrosarcoma of bone; acute leukemia, malignant lymphoma, chronic leukemia; hepatic hemangioma, islet cell carcinoid, neuroblastoma, myxoma, neck Ministry of metastatic cancer, cardia; independently,

Wherein said anti-aging drugs, including prevention memory loss, insomnia drugs, Alzheimer's disease, Parkinson's disease, osteoporosis, diabetes or cardiovascular disease: independently,

Wherein the cosmetic include skin whitening, skin water retention, reduce or eliminate wrinkles, elasticity enhancement, acne, freckle, remove scarring or skin rejuvenation cosmetics.

Description  translated from Chinese

Containing chlorine dioxide apoptosis-inducing agents and their use in the manufacture of cosmetic or anti-aging or anti-tumor drugs TECHNICAL FIELD

The present invention belongs to the field of anti-aging and cancer treatment, and more particularly by inducing senescence and tumor cells undergo apoptosis, thus the old method of treating tumors and rejuvenation, as well as in the manufacture of chlorine dioxide used in mammalian apoptosis-inducing agent or cosmetic medicament.

https://www.google.com/patents/WO2016074203A1?cl=en


G2Voice Broadcast #89: All the “FDA & EPA Approved” applications for Chlorine Dioxide and Sodium Chlorite

Sunday May 27th, 2018

10 AM CST

Let’s change the world together!

Archbishop Mark S. Grenon

 



 

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